Serotypes and virulence genes of extraintestinal pathogenic Escherichia coli isolates from diseased pigs in China

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• 作者：Chen Tan¹ ; Xibiao Tang¹ ; Xuan Zhang ; Yi Ding ; Zhanqin Zhao ; Bin Wu ; ^{wub@mail.hzau.edu.cn} ; Xuwang Cai ; Zhengfei Liu ; Qigai He ; Huanchun Chen
• 关键词：Extraintestinal pathogenic Escherichia coli ; Pigs ; Virulence ; China
• 刊名：The Veterinary Journal
• 出版年：2012
• 出版时间：June, 2012
• 年：2012
• 卷：192
• 期：3
• 页码：483-488
• 全文大小：189 K

文摘

Extraintestinal pathogenic Escherichia coli (ExPEC) isolates were detected in 315/3127 (10.1 % ) diseased pigs from 19 provinces of China; the frequency of isolation increased from 3.1 % in 2004 to 14.6 % in 2007. All isolates were characterised for O serogroups, haemolysis, phenotypic and genotypic antimicrobial resistance, virulence genes and pathogenicity. The most prevalent serogroups were O161, O8, O11, O138, O101 and O26; 83/315 (26.3 % ) isolates were haemolytic. Forty percent of isolates in phylogenetic groups B2 and D were highly virulent porcine ExPEC strains. Thirty-three putative extraintestinal virulence factor genes that are normally associated with human and/or avian ExPEC strains were widely present in porcine isolates. These results indicate that ExPEC are prevalent in pigs in China and represent a potential public health threat.