Establishment of a new pull-out strength testing method to quantify early osseointegration—An experimental pilot study

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• 作者：J. Nonhoff^a ; ¹ ; T. Moest^b ; ¹ ; ^{Tobias.Moest@uk-erlangen.de" class="auth_mail" title="E-mail the corresponding author} ; Christian Martin Schmitt^b ; T. Weisel^a ; S. Bauer^a ; K.A. Schlegel^b
• 关键词：Dental implant ; Osseointegration ; Experimental animal model
• 刊名：Journal of Cranio-Maxillofacial Surgery
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：43
• 期：10
• 页码：1966-1973
• 全文大小：1718 K

文摘

The animal study aims to evaluate a new experimental model for measuring sole the influence of the surface characteristics independent from implant macro-design on the level of osseointegration by registering the pull-out strength needed for removal of experimental devices with different surfaces from artificial defects.

Material and methods

Seventy-two test bodies (36 with the FRIADENT^® plus surface, 36 with the P15/HAp biofunctionalized surface) were inserted in six adult domestic pigs with artificial calvarial defects. The experimental devices were designed to fit in the defects leaving a gap between the test body and the local bone. After 21 days of healing, the animals were sacrificed and the test bodies were pulled out with a standardised reproducible pull-out device measuring the pull-out strength. The pull-out strength for both groups was compared.

Results

Twenty-one days after insertion a mean force of 412 ± 142 N for the P15/HAp group and 183 ± 105 N for the FRIADENT^® plus group was measured for the removal of the specimens from the calvarial bone. The difference between the groups was statistically significant (p < 0.0001).

Conclusion

The experimental set-up seems to be a suitable method when measuring the impact of implant surfaces on the early stage of osseointegration.