Manic Episode Induced by Sertraline in a Patient with an Obsessive Compulsive Disorder

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• 作者：P. Quandt¹ ; N. Casanova¹ ; E. Vera-Barrios² ; M. Puga²
• 刊名：European Psychiatry
• 出版年：2015
• 出版时间：28-31 March 2015
• 年：2015
• 卷：30
• 期：supp_S1
• 页码：1503
• 全文大小：50 K

文摘

Apropos of a case we show that antidepressant drugs may cause a switch phenomenon in patients diagnosed with a psychiatric illness other than bipolar disorder.

ec_2">Objective

To describe a case of antidepressant-induced mania in a patient with obsessive compulsive disorder (OCD).

ec_3">Methods

X is an 18 year-old male who presented obsession with books and compulsive reading. He went to the psychiatric consultation and initiated treatment with sertraline 25mg. 24 hours later he began with soliloquies, restlessness, verbosity, increased performance of activities without purpose and persistent insomnia.

ec_4">Results

After the antidepressant was removed, the manic symptoms disappeared and the patient remained euthymic. Treatment with risperidone 1 mg was established and the obsessions and compulsions partially improved.

ec_5">Conclusions

This case raises the hypothesis of a possible comorbidity between OCD and bipolar disorder.