Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats
详细信息 查看全文
- 作者：Mohammad Ejaz Ahmed&dagger ; ; Donovan Tucker&dagger ; ; Yan Dong ; Yujiao Lu ; Ningjun Zhao ; Ruimin Wang ; Quanguang Zhang ; qzhang@augusta.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：BrdU ; 5-bromodeoxyuridine ; DTT ; dithiotheitol ; ip ; intraperitoneally ; MB ; Methylene Blue ; PBS ; phosphate-buffered saline ; PFA ; paraformaldehyde ; PT ; photothrombotic
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：12 November 2016
- 年：2016
- 卷：336
- 期：Complete
- 页码：39-48
- 全文大小：1416 K
文摘
- •
Methylene Blue ameliorates sensorimotor deficits after photothrombotic (PT) stroke.
- •
Methylene Blue stimulates neurogenesis in the peri-infarct region after PT stroke.
- •
Methylene Blue reduces neuroinflammation in the peri-infarct region after PT stroke.
- •
Methylene Blue treatment promotes mitochondrial activity and ATP production.
- •
Methylene Blue treatment reduces infarct volume after PT stroke.