A simple and sensitive liquid chromatography-tandem mass spectrometry method for trans-ε-viniferin quantification in mouse plasma and its application to a pharmacokinetic study in mice
刊名:Journal of Pharmaceutical and Biomedical Analysis
出版年:2017
出版时间:5 February 2017
年:2017
卷:134
期:Complete
页码:116-121
全文大小:647 K
卷排序:134
文摘
First LC–MS/MS method for trans-ε-viniferin quantification in mouse plasma. A simple protein precipitation that allowed for efficient/reproducible recovery yields was used. The small plasma volume (10 μl) supports the ability to examine pharmacokinetics in mice.