Recent developments in the synthesis of zoanthamine alkaloids

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• 作者：Fumihiko Yoshimura ; ^{fumi@sci.hokudai.ac.jp" class="auth_mail} ; Keiji Tanino ; Masaaki Miyashita
• 关键词：Zoanthamine alkaloids ; Total synthesis ; Quaternary asymmetric carbon atom ; Aminoacetal
• 刊名：Tetrahedron Letters
• 出版年：30 April 2014
• 年：2014
• 卷：55
• 期：18
• 页码：2895-2903
• 全文大小：1554 K

文摘

This review provides a compilation of the most recent synthetic approaches and total syntheses of zoanthamine alkaloids, which are structurally unique heptacyclic marine natural products that display a range of interesting biological activities. This review is focused on synthetic methodologies for the construction of the three adjacent quaternary asymmetric carbon atoms on the cyclohexane ring (C-ring) of these compounds. The literature covered in this review dates from 2008 to the end of 2013.