Significant Mitral Regurgitation Left Untreated at the Time of Aortic Valve Replacement: A Comprehensive Review of a Frequent Entity in the Transcatheter Aortic Valve Replacement Era

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• 作者：Luis Nombela-Franco ; MD^&lowast ; ; ^&dagger ; ; Henrique Barbosa Ribeiro ; MD^&lowast ; ; Marina Urena ; MD^&lowast ; ; Ricardo Allende ; MD^&lowast ; ; Ignacio Amat-Santos ; MD^&lowast ; ; Robert DeLarochelliè ; re ; MD^&lowast ; ; Eric Dumont ; MD^&lowast ; ; Daniel Doyle ; MD^&lowast ; ; Hugo DeLarochelliè ; re ; MS^&lowast ; ; Jerô ; me Laflamme ; MS^&lowast ; ; Louis Laflamme ; MS^&lowast ; ; Eulogio Garcí ; a ; MD^&dagger ; ; Carlos Macaya ; MD ; PhD^&dagger ; ; Pilar Jimé ; nez-Quevedo ; MD^&dagger ; ; Mé ; lanie Cô ; té ; MSc^&lowast ; ; Sebastien Bergeron ; MD^&lowast ; ; Jonathan Beaudoin ; MD^&lowast ; ; Philippe Pibarot ; PhD^&lowast ; ; Josep Rodé ; s-Cabau ; MD^&lowast ; ; ^{josep.rodes@criucpq.ulaval.ca" class="auth_mail}
• 关键词：aortic stenosis ; mitral regurgitation ; percutaneous therapy ; transcatheter aortic valve implantation
• 刊名：Journal of the American College of Cardiology
• 出版年：24 June 2014
• 年：2014
• 卷：63
• 期：24
• 页码：2643-2658
• 全文大小：1968 K

文摘

Significant mitral regurgitation (MR) is frequent in patients with severe aortic stenosis (AS). In these cases, concomitant mitral valve repair or replacement is usually performed at the time of surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) has recently been considered as an alternative for patients at high or prohibitive surgical risk. However, concomitant significant MR in this setting is typically left untreated. Moderate to severe MR after aortic valve replacement is therefore a relevant entity in the TAVR era. The purpose of this review is to present the current knowledge on the clinical impact and post-procedural evolution of concomitant significant MR in patients with severe AS who have undergone aortic valve replacement (SAVR and TAVR). This information could contribute to improving both the clinical decision-making process in and management of this challenging group of patients.