Amphiregulin enhances VEGF-A production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR-206 via FAK/c-Src/PKCδ pathway

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• 作者：Chao-Qun Wang^a ; ¹ ; Yu-Wen Huang^b ; ¹ ; Shih-Wei Wang^c ; Yuan-Li Huang^d ; Chun-Hao Tsai^e ; ^f ; Yong-Ming Zhao^g ; Bi-Fei Huang^a ; Guo-Hong Xu^h ; Yi-Chin Fongⁱ ; ^j ; Chih-Hsin Tang^b ; ^d ; ^e ; ^{chtang@mail.cmu.edu.tw}
• 关键词：Amphiregulin ; VEGF-A ; Angiogenesis ; miR-206
• 刊名：Cancer Letters
• 出版年：2017
• 出版时间：28 January 2017
• 年：2017
• 卷：385
• 期：Complete
• 页码：261-270
• 全文大小：3204 K
• 卷排序：385

文摘

Amphiregulin induces VEGF expression. Amphiregulin promotes angiogenesis. FAK, c-Src and PKCδ pathways are mediated amphiregulin effects. Amphiregulin induces VEGF via inhibiting miR-206.