High-resolution SPECT for small-animal imaging

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• 作者：Yu-Jin QI
• 关键词：Small-animal SPECT ; Molecular imaging ; Pinhole collimation ; Gamma camera
  CLC numbers ; R817.4 ; TB811⁺.2
• 刊名：Nuclear Science and Techniques
• 出版年：2006
• 出版时间：June 2006
• 年：2006
• 卷：17
• 期：3
• 页码：164-169
• 全文大小：1012 K

文摘

This article presents a brief overview of the development of high-resolution SPECT for small-animal imaging. A pinhole collimator has been used for high-resolution animal SPECT to provide better spatial resolution and detection efficiency in comparison with a parallel-hole collimator. The theory of imaging characteristics of the pin-hole collimator is presented and the designs of the pinhole aperture are discussed. The detector technologies used for the development of small-animal SPECT and the recent advances are presented. The evolving trend of small-animal SPECT is toward a multi-pinhole and a multi-detector system to obtain a high resolution and also a high detection efficiency.