Fine needle aspiration cytology (FNAC) of salivary gland tumours: Repeat aspiration provides further information in cases with an unclear initial cytological diagnosis

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• 作者：Peter A. Brennan ; Benedict Davies ; David Poller ; Zoe Mead ; Duncan Bayne ; Roberto Puxeddu ; Rachel S. Oeppen
• 关键词：Salivary gland ; Tumour ; Fine needle aspiration cytology ; Diagnosis ; Head and neck
• 刊名：British Journal of Oral and Maxillofacial Surgery
• 出版年：2010
• 出版时间：January 2010
• 年：2010
• 卷：48
• 期：1
• 页码：26-29
• 全文大小：99 K

文摘

Introduction

Fine needle aspiration cytology (FNAC) for salivary gland tumours requires expertise in interpretation. When a diagnosis is not clear (despite a cellular aspirate), published work is lacking on the value of repeating the test.

Methods

A retrospective study of 135 patients who had FNAC followed by definitive excision for a suspected salivary gland tumour. Accuracy was compared among those requiring repeat FNAC on one more occasion because of a non-diagnostic initial cytology report.

Results

33 patients (24 % of study group) had repeat FNAC. A definite cytological diagnosis was subsequently made in 27/33 patients (82 % ). The sensitivity (84 % ) and specificity (93 % ) of repeat FNAC in distinguishing benign from malignant tumours was similar to initial FNAC (70 % and 95 % , respectively).

Conclusions

Repeat FNAC may provide a cytological diagnosis in cases where the initial diagnosis is not clear, although cytology should be used in conjunction with other investigations of salivary tumours, including image-guided biopsy examination where appropriate. Ideally salivary gland FNAC should be interpreted by a specialist pathologist.