LC-ESI-MS/MS analysis of Asparagus racemosus Willd. roots and its protective effects against t-BHP induced oxidative stress in rats
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- 作者：G.V. Jayashree ; Kandikattu Hemanth Kumar ; K. Krupashree ; P. Rachitha ; Farhath Khanum ; farhathkhanum@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：LC&ndash ; ESI&ndash ; MS/MS ; t-BHP ; Hepatotoxicity ; Oxidative stress ; DNA damage ; Protein carbonyls
- 刊名：Industrial Crops & Products
- 出版年：2015
- 出版时间：30 December 2015
- 年：2015
- 卷：78
- 期：Complete
- 页码：102-109
- 全文大小：1683 K
文摘
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Metabolites were identified by LC–ESI–MS/MS from Asparagus racemosus roots methanolic extract (AME).
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tert-Butyl hydroperoxide (t-BHP) induced tissue oxidative stress was ameliorated by AME supplementation.
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AME administration to rats inhibited t-BHP induced ROS and protein carbonyls.
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AME inhibited t-BHP induced hepatic and WBC DNA damage.