Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae
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- 作者：Alfonso Olaya-Abrila ; b ; Rafael Prados-Rosalesc ; Michael J. McConnellb ; d ; Reyes Martí ; n-Peñ ; ab ; d ; José ; Antonio Gonzá ; lez-Reyese ; Irene Jimé ; nez-Munguí ; aa ; b ; Lidia Gó ; mez-Gascó ; na ; b ; Javier Ferná ; ndezf ; José ; L. Luque-Garcí ; ag ; Carlos Garcí ; a-Lidó ; ng ; Hé ; ctor Esté ; vezg ; Jeró ; nimo Pachó ; nb ; d ; Ignacio Obandoh ; Arturo Casadevallc ; Liise-anne Pirofskii ; Manuel J. Rodrí ; guez-Ortegaa ; b ; mjrodriguez@uco.es" class="auth_mail
- 关键词：Pneumococcus ; Proteomics ; Membrane vesicles ; Extracellular vesicles ; Vaccine ; Surface proteins
- 刊名：Journal of Proteomics
- 出版年：25 June 2014
- 年：2014
- 卷：106
- 期：Complete
- 页码：46-60
- 全文大小：1795 K
文摘
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Pneumococcus produces membrane vesicles that are released to the milieu.
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Proteomics show that they are more enriched in lipoproteins than the cell membrane.
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Membrane vesicles induce protection against pneumococcal infection in mice.