Clinical and quality of life data correlation with a single-optic accommodating intraocular lens

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• 作者：Mar&#237 ; a L. Ramó ; n^a ; ^b ; David P. Piñ ; ero^a ; ^b ; ^c ; ^{david.pinyero@ua.es} ; Francisco J. Blanes-Mompó ; ^a ; ^b ; Rafael J. Pé ; rez-Cambrod&#237 ; ^a ; ^b
• 关键词：Crystalens ; Accommodating intraocular lens ; Quality of life ; Intraocular aberration ; Defocus curve ; Cataract surgery
• 刊名：Journal of Optometry
• 出版年：2013
• 出版时间：January-March, 2013
• 年：2013
• 卷：6
• 期：1
• 页码：25-35
• 全文大小：503 K

文摘

Purpose

To examine a single-optic accommodating intraocular lens (IOL) visual performance by correlating IOL implanted eyes¡¯ defocus curve with the intraocular aberrometric profile and the impact on the quality of life (QOL).

Methods

Prospective consecutive case series study including a total of 25 eyes of 14 patients with ages ranging between 52 and 79 years old. All cases underwent cataract surgery with implantation of the single-optic accommodating IOL Crystalens HD (Bausch & Lomb). Distance and near visual acuity outcomes, intraocular aberrations, the defocus curve and QOL (NEI VFQ-25) were evaluated 3 months after surgery.

Results

A significant improvement in distance visual acuity was found postoperatively (p = 0.02). Mean postoperative LogMAR uncorrected near visual acuity was 0.44 ¡À 0.23 (20/30). 60 % of eyes had a postoperative addition between 0 and 1.5 diopters (D). The defocus curve showed an area of maximum visual acuity for the levels of defocus corresponding to distance and intermediate vision (?1 to +0.5 D). Postoperative intermediate visual acuity correlated significantly some QOL indices (r ¡Ý 0.51, p ¡Ü 0.03; difficulty in going down steps or seeing how people react to things that patient says) as well as with J₀ component of manifest cylinder. Postoperative distance-corrected near visual acuity correlated significantly with age (r = 0.65, p < 0.01).

Conclusions

This accommodating IOL seems to be able to restore the distance visual function as well as to provide an improvement in intermediate and near vision with a significant impact on patient's QOL, although limited by age and astigmatism. Future studies with larger sample sizes should confirm all these trends.