Variation in the use of granulocyte-colony stimulating factor for dose dense paclitaxel: A single institution retrospective study
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- 作者：Romualdo Barroso-Sousaa ; Flavia Rocha Paesb ; Ines Vaz-Luisa ; Rafael Borges Batistab ; Rafael Brant Costab ; Katya Loska ; Kristen Camusoa ; Otto Metzger-Filhoa ; Melissa E. Hughesa ; Craig A. Bunnella ; Mehra Golshanc ; Eric P. Winera ; Nancy U. Lina ; nancy_li@dfci.harvard.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dose-dense chemotherapy ; Paclitaxel ; Colony stimulating factors
- 刊名：The Breast
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：30
- 期：Complete
- 页码：136-140
- 全文大小：318 K
文摘
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There is a substantial variation in the use of prophylactic G-CSF during dose-dense paclitaxel in clinical practice.
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Reasons for omitting prophylactic G-CSF during DD-T included high baseline absolute neutrophil count and pain.
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The omission of prophylactic G-CSF during dose-dense paclitaxel was not associated with treatment delay or adverse events.