Accuracy of MR markers for differentiating Progressive Supranuclear Palsy from Parkinson's disease
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- 作者：Stefano Zanignia ; b ; Giovanna Calandra-Buonaurab ; c ; David Neil Mannersa ; b ; Claudia Testaa ; b ; Dino Gibertonib ; d ; Stefania Evangelistia ; b ; Luisa Sambatib ; c ; Maria Guarinoe ; Patrizia De Massisf ; Laura Ludovica Gramegnaa ; b ; Claudio Bianchinia ; b ; Paola Ruccib ; d ; Pietro Cortellib ; c ; Raffaele Lodia ; b ; raffaele.lodi@unibo.it" class="auth_mail" title="E-mail the corresponding author ; Caterina Tonona ; b
- 关键词：AUC ; area under the curve ; FA ; Fractional Anisotropy ; MCP ; middle cerebellar peduncle ; MD ; Mean Diffusivity ; MRPI ; MR Parkinsonism Index ; P/M ; pons to midbrain ratio ; PD ; idiopathic Parkinson's disease ; PSP-RS ; Progressive Supranuclear Palsy-Richardson's Syndrome ; ROC ; receiver operating characteristics ; SCP ; superior cerebellar peduncle
- 刊名：NeuroImage: Clinical
- 出版年：2016
- 出版时间：2016
- 年：2016
- 卷：11
- 期：Complete
- 页码：736-742
- 全文大小：543 K
文摘
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We compared quantitative brain MR markers accuracy to differentiate advanced stages of PSP-RS from PD.
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Quantitative morphometric, DTI and volumetric data showed moderate-high accuracies.
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Midbrain area alone best discriminated advanced PSP-RS from PD (99%).
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Midbrain area evaluation should be added to brain MR protocols for parkinsonisms.