Antimicrobial potential of Glycyrrhiza glabra roots

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• 作者：Vivek K. Gupta ; Atiya Fatima ; Uzma Faridi ; Arvind S. Negi ; Karuna Shanker ; J.K. Kumar ; Neha Rahuja ; Suaib Luqman ; Brijesh S. Sisodia ; Dharmendra Saikia ; M.P. Darokar ; Suman P.S. Khanuja
• 关键词：Licorice ; Glycyrrhiza glabra ; Glabridin ; Antibacterial ; Antitubercular
• 刊名：Journal of Ethnopharmacology
• 出版年：2008
• 出版时间：5 March 2008
• 年：2008
• 卷：116
• 期：2
• 页码：377-380
• 全文大小：146 K

文摘

The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 μg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H₃₇Ra and H₃₇Rv strains at 29.16 μg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.