Factors associated with intention to engage in self-protective behavior: The case of over-the-counter acetaminophen products

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• 作者：R.V. Sawant ; M.S.^a ; R.K. Goyal ; M.S.^b ; S.S. Rajan ; M.H.A. ; M.S. ; Ph.D.^c ; H.K. Patel ; Ph.D.^a ; E.J. Essien ; M.D. ; Dr.P.H.^a ; S.S. Sansgiry ; Ph.D.^a ; ^{ssansgiry@uh.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Risk cognition ; Protective behavior ; Acetaminophen ; Liver injury ; Liver damage ; Appropriate use of OTC products
• 刊名：Research in Social and Administrative Pharmacy
• 出版年：2016
• 出版时间：March-April 2016
• 年：2016
• 卷：12
• 期：2
• 页码：327-335
• 全文大小：778 K

文摘

Inappropriate use of acetaminophen products is a concern due to the severe liver damage associated with intentional or accidental overdose of these products. In 2009, the U.S. Food and Drug Administration (FDA) issued more severe organ-specific warnings for the acetaminophen Drug Facts label to improve protective behavior among patients. However, it is not clear how patients react to such interventions by the FDA.

Objective

The objective of this study was to evaluate the factors influencing patients' intention to engage in protective behavior while using acetaminophen products after reading the Drug Facts label. The study specifically looked at the relationship between four Protection Motivation Theory-based risk cognition factors and the intention to engage in protective behavior.

Methods

An experimental, cross-sectional, field study was conducted using self-administered questionnaires at four community pharmacies in Houston, TX. Two hundred surveys were collected from adults visiting the selected pharmacy stores. Participants were exposed to a simulated label (i.e. Drug Facts label) containing organ-specific warnings for over-the-counter (OTC) acetaminophen products. Risk cognition measures (i.e. measures of perceived severity, perceived vulnerability, response efficacy, and self-efficacy) and measures of intention to engage in protective behavior (always reading warnings, using products with more caution, and consulting a pharmacist/physician) were recorded. Pearson correlation and multiple linear regression analyses, controlling for demographic and behavioral characteristics of the participants, were performed.

Results

Bivariate analyses indicated that an increase in perceived severity, perceived vulnerability and response efficacy were associated with a higher intention to engage in protective behavior. Findings from the multiple regression indicated that increase in perceived severity of liver damage, belonging to a non-healthcare occupation, no history of acetaminophen use and no history of alcohol consumption were associated with a higher intention to engage in protective behavior.

Conclusion

Higher risk cognition of liver damage associated with inappropriate use of OTC acetaminophen products leads to greater intention to engage in protective behavior while using such products. Developing interventions targeted towards improving reading and adhering to the Drug Facts label could improve risk cognition, and thus improve patients' intention to engage in protective behavior. Regular acetaminophen users, heavy alcohol consumers and healthcare professionals might need other interventions apart from the Drug Facts label to improve their likelihood to engage in protective behavior.