Comparative genomics study for the identification of drug and vaccine targets in Staphylococcus aureus: MurA ligase enzyme as a proposed candidate
详细信息 查看全文
- 作者：Soma Ghosha ; Jyoti Pravab ; Himanshu Bhusan Samalb ; Mrutyunjay Suara ; Rajani Kanta Mahapatraa ; rmahapatra@kiitbiotech.ac.in" class="auth_mail
- 关键词：Staphylococcus aureus ; Computational comparative genomics ; KEGG ; Drug targets ; MurA enzyme
- 刊名：Journal of Microbiological Methods
- 出版年：June 2014
- 年：2014
- 卷：101
- 期：Complete
- 页码：1-8
- 全文大小：833 K
文摘
- •
Comparative genomics study to predict drug and vaccine targets in S. aureus
- •
94 proteins are identified as non-homologous essential proteins.
- •
19 proteins prioritized as vaccine candidates whereas 34 as drug targets
- •
Homology modeling and in silico docking study of the drug target MurA enzyme