Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development
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- 作者：Anamika Singh
- 关键词：epicardium ; proepicardium ; Hippo signaling ; Yap ; Taz ; epithelial to mesenchymal transition (EMT)
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：17 May 2016
- 年：2016
- 卷：15
- 期：7
- 页码：1384-1393
- 全文大小：4349 K
文摘
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- <p id="p0010">Hippo signaling components are expressed in the developing proepicardium and epicardiump>
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- <p id="p0015">Genetic deletion of Yap and Taz leads to coronary vasculature defectsp>
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- <p id="p0020">Yap and Taz regulate epicardial cell proliferation, EMT, and cell fate specificationp>