Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells
详细信息 查看全文
- 作者：Bastian Zimmer
- 刊名：Stem Cell Reports
- 出版年：2016
- 出版时间：14 June 2016
- 年：2016
- 卷：6
- 期：6
- 页码：858-872
- 全文大小：4656 K
文摘
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- <p id="p0010">Defined, cGMP-ready protocol to derive anterior pituitary-lineage cells from hPSCsp>
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- <p id="p0015">FGF8 and BMP2 patterning enables enrichment for specific hormone-producing cellsp>
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- <p id="p0020">Pituitary cells secrete multiple hormones and respond to physiological stimulip>
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- <p id="p0025">hPSC-pituitary cells partially rescue a rat model of hypopituitarismp>