Intraoperative assessment of sentinel lymph node by one-step nucleic acid amplification in breast cancer patients after neoadjuvant treatment reduces the need for a second surgery for axillary lymph node dissection

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• 作者：Martin Espinosa-Bravo^a ; ^{maespino@vhebron.net} ; Joaquin Navarro-Cecilia^b ; ^{dr.jnavarro@hotmail.com} ; Manuel Ramos Boyero^c ; ^{mramos@usal.es} ; Sebastian Diaz-Botero^a ; ^{sdiazmd@gmail.com} ; Basilio Due&ntilde ; as Rodr&iacute ; guez^b ; ^{bdr@quesadasolidaria.org} ; Carolina Luque Ló ; pez^d ; ^{caluque@gmail.com} ; Teresa Ramos Grande^c ; ^{tramos@usal.es} ; Ricardo Ruano Perez^e ; ^{rruanoperez@gmail.com} ; Vicente Peg^f ; ^{vpeg@vhebron.net} ; Isabel T. Rubio^a ; ^{irubio@vhio.net}
• 关键词：Breast cancer ; Neoadjuvant chemotherapy ; Sentinel lymph node ; OSNA assay
• 刊名：The Breast
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：31
• 期：Complete
• 页码：40-45
• 全文大小：558 K
• 卷排序：31

文摘

OSNA detect positives SLNs after NAC as accurately as conventional pathology. The false negative rate of FS after NAC was 18.5% with a sensitivity of 81.5%. Intraoperative definitive assessment by OSNA reduces the need for a second surgery.