刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:26 February 2017
年:2017
卷:484
期:1
页码:64-70
全文大小:2775 K
卷排序:484
文摘
Rifampin inhibited Ti-induced osteolysis and osteoclastogenesis in vivo. Rifampin suppressed osteoclast differentiation and bone resorption in a dose-dependent manner. Rifampin significantly reduced the expression of osteoclast-specific markers in vitro. RANKL-induced p38 and NF-κB signaling may be involved behind the effects of rifampin treatment on osteoclastogenesis.