Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis
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- 作者：Raoul Belzeauxa ; b ; c ; raoul.belzeaux@mail.mcgill.ca" class="auth_mail" title="E-mail the corresponding author ; Chien-Wei Lind ; Ying Dingd ; Auré ; lie Bergone ; El Ché ; rif Ibrahimb ; c ; Gustavo Tureckia ; George Tsengd ; Etienne Sibillef
- 关键词：Mood disorder ; Antidepressant ; Inflammation ; MicroRNA ; Gene network
- 刊名：Journal of Psychiatric Research
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：81
- 期：Complete
- 页码：119-126
- 全文大小：561 K
文摘
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Global gene coexpression network is not disrupted in Major Depression.
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9 modules of the network are associated with antidepressant response.
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Modules pathways analysis suggest the involvement of inflammatory processes.
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Numerous microRNAs are predicted to regulate these modules.