An efficient catalyst system for diaryl ether synthesis from aryl chlorides

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• 作者：Harkal ; Surendra ; Kumar ; Kamal ; Michalik ; Dirk ; Zapf ; Alexander ; Jackstell ; Ralf ; Rataboul ; Franck ; et. al.
• 关键词：Aryl chlorides ; Aryl ethers ; Etherification ; Palladium ; Phosphines
• 刊名：Tetrahedron Letters
• 出版年：2005
• 出版时间：May 2, 2005
• 年：2005
• 卷：46
• 期：18
• 页码：3237-3240
• 全文大小：137 K

文摘

The combination of 2-phosphino-substituted N-arylpyrroles or related indoles (cataCXium^®P) and Pd(OAc)₂ allows for efficient cross-coupling reactions of aryl chlorides and phenols to give diaryl ethers. A variety of aryl and heteroaryl chlorides can be coupled with substituted phenols showing unprecedented catalyst turnover numbers.