A developmental toxicity study of 3S, 3′S-Astaxanthin in New Zealand white rabbits
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- 作者：Steffen Schneidera ; Werner Mellerta ; Stefan Schulteb ; Bennard van Ravenzwaaya ; bennard.ravenzwaay@basf.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Developmental toxicity ; Astaxanthin ; Rabbit
- 刊名：Food and Chemical Toxicology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：90
- 期：Complete
- 页码：95-101
- 全文大小：376 K
文摘
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Synthetic Astaxanthin was investigated in a regulatory compliant developmental toxicity study in New Zealand White rabbits.
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Animals were treated from gestational days 6–28 by gavage with an Astaxanthin powder formulation or a blank formulation.
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Doses up to 400 mg/kg body weight throughout pregnancy did not indicate any potential risk of developmental toxicity.