Lateralization of seizure-onset zone (SOZ) during electroencephalography (EEG) monitoring in people with bilateral potentially epileptogenic lesions is a frequent clinical dilemma.

Two different Bayesian approaches for estimating the number of consecutive ipsilateral seizures required to lateralize the SOZ to a given lower limit of 95% credible interval (LLI, assuming continuous prior distribution), or to a given posterior probability (assuming mixture of discrete and continuous prior probabilities) are developed.

Calculations based on multiple different values for the parameters are provided, which are deemed to represent different clinical situations.