Clinical factors predict surgical outcomes in pediatric MRI-negative drug-resistant epilepsy
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- 作者：Ravindra Aryaa ; Ravindra.Arya@cchmc.org" class="auth_mail" title="E-mail the corresponding author ; James L. Leachb ; Paul S. Horna ; c ; Hansel M. Greinera ; Michael Gelfandb ; Anna W. Byarsa ; Todd M. Arthura ; Jeffrey R. Tenneya ; Sejal V. Jaina ; Leonid Rozhkova ; Hisako Fujiwaraa ; Douglas F. Rosea ; Francesco T. Manganod ; Katherine D. Hollanda
- 关键词：Childhood epilepsy ; Drug-resistant epilepsy ; MRI negative epilepsy ; Epilepsy surgery ; Outcomes
- 刊名：Seizure
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：41
- 期：Complete
- 页码：56-61
- 全文大小：290 K
文摘
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12/47 children with MRI-negative epilepsy were seizure-free 2.8 years after surgery.
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50% of children with single semiology and concordant ictal EEG were seizure free.
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Clinical factors determine seizure outcomes in children with MRI-negative epilepsy.
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Predictors: low seizure frequency, later age of onset, fewer pre-surgical AEDs.
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ILAE type I-B cortical dysplasia was found in 17/47 patients.