The Rhesus Monkey Connectome Predicts Disrupted Functional Networks Resulting from Pharmacogenetic Inactivation of the Amygdala
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- 作者：David S. Grayson1 ; 2 ; 3 ; Eliza Bliss-Moreau1 ; 4 ; Christopher J. Machado1 ; 4 ; Jeffrey Bennett1 ; 2 ; 4 ; Kelly Shen5 ; Kathleen A. Grant6 ; Damien A. Fair7 ; 8 ; 9 ; David G. Amaral1 ; 2 ; 3 ; 4 ; dgamaral@ucdavis.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Neuron
- 出版年：2016
- 出版时间：20 July 2016
- 年：2016
- 卷：91
- 期：2
- 页码：453-466
- 全文大小：5437 K
文摘
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The amygdala was remotely inactivated using the DREADDs technique
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Coupled activity was disrupted throughout cortical networks involving the amygdala
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Altered global dynamics increased coupling between other topologically distant areas
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Simulated anatomical lesions are correlated with diverse network effects