Social behaviour and stress reactivity were compared in calves reared with cow-contact and calves reared with peer-contact only. Social Isolation and confrontation (with an adult cow) tests were conducted on 29 dairy farms in Switzerland and Germany. ‘Cow-contact’ calves show more adaptive social behaviour (submission during confrontation) than calves housed in peer groups. Calves reared with cow-contact show lowered cardiac response to isolation compared to calves reared with peer-contact only. The rearing system did not affect the behavioural and cortisol stress response.