Cytokine Profile of Engraftment Syndrome in Pediatric Hematopoietic Stem Cell Transplant Recipients
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- 作者：Pooja Khandelwal1 ; Pooja.khandelwal@cchmc.org" class="auth_mail" title="E-mail the corresponding author ; Sabine Mellor-Heineke1 ; Najibah Rehman1 ; Adam Lane2 ; Kristi Smiley1 ; Joyce Villanueva1 ; Rebecca A. Marsh1 ; Michael S. Grimley1 ; Stella M. Davies1 ; Alexandra H. Filipovich1
- 关键词：Engraftment syndrome ; Cytokine ; IL-1β ; Acute GVHD ; Cytokine storm
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：4
- 页码：690-697
- 全文大小：1299 K
文摘
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Isolated engraftment syndrome has a different cytokine profile compared with acute GVHD.
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High levels of IL-1β suggests that isolated engraftment syndrome is an inflammasome mediated process.
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Macrophages might be the effector cells of engraftment syndrome.