文摘
A suite of interactors for the testis-specific form of Importin 13 were identified, and a number validated in mouse testis Translation initiation factor EIF4G2 and High Mobility Group 20A protein were identified as Importin 13 nuclear export cargo The testis-specific Importin 13 inhibited nuclear accumulation of all cargo examined, including glucocorticoid receptor Imp13 was detected for the first time in spermatozoa, along with specific binding partners, implying a role in mature sperm