ar0005">ALS: multiple pathogenic mechanisms that share TDP-43 deposits as common trait.
ar0010">Most of genes related to ALS are involved in RNA metabolism, endosome trafficking, autophagy and energy metabolism.
ar0015">C9ORF72 expansion plays a common role in sporadic and familiar ALS pathogenesis.
ar0020">ALS is a multi-system disease with important metabolic alterations.
ar0025">Genes, environment and toxins are key factors to unveil the enigma of motor neuron degeneration.