Laminin receptor is an interacting partner for viral outer capsid protein VP5 in grass carp reovirus infection
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- 作者：Hao Wang ; Fei Yu ; Jiale Li ; Liqun Lu ; lqlv@shou.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Grass carp reovirus ; Laminin receptor ; Outer capsid ; Protein&ndash ; protein interaction ; Infection inhibition
- 刊名：Virology
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：490
- 期：Complete
- 页码：59-68
- 全文大小：10128 K
文摘
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37/67-kDa laminin receptor (LamR) interacts with VP5 of GCRV.
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LamR is a cellular attachment protein for GCRV.
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Knock-down of LamR expression resulted in inhibition of viral infection.
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Polyclonal antibody against LamR inhibits GCRV infection dose-dependently.