B cell receptor induced Fc receptor-like 5 expression is mediated by multiple signaling pathways converging on NF-κB and NFAT
详细信息 查看全文
- 作者：Bazarragchaa Damdinsuren ; Jessica Dement-Brown ; Huifang Li ; Mate Tolnay ; mate.tolnay@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ab ; antibody ; BCR ; B cell antigen receptor ; CsA ; cyclosporine A ; EMSA ; electrophoretic mobility shift assay ; FCRL ; Fc receptor-like ; TSS ; transcription start site
- 刊名：Molecular Immunology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：73
- 期：Complete
- 页码：112-121
- 全文大小：1877 K
文摘
- •
Human FCRL5 is induced upon B cell antigen receptor stimulation.
- •
FCRL5 induction is delayed and requires sustained stimulation.
- •
Induced FCRL5 expression is mediated by multiple signaling pathways.
- •
Transcription factors NF-κB and NFAT regulate FCRL5 transcription.