Antagonism of V1b receptors promotes maternal motivation to retrieve pups in the MPOA and impairs pup-directed behavior during maternal defense in the mpBNST of lactating rats
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- 作者：Doris S. Bayerl doris.bayerl@ur.de" class="auth_mail" title="E-mail the corresponding author ; Veronika Kaczmarek veronika.kaczmarek@campus.lmu.de" class="auth_mail" title="E-mail the corresponding author ; Benjamin Jurek benjamin.jurek@ur.de" class="auth_mail" title="E-mail the corresponding author ; Erwin H. van den Burg erwinregensburg@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Inga D. Neumann inga.neumann@ur.de" class="auth_mail" title="E-mail the corresponding author ; Barbara M. Gaß ; ner barbara.gassner@stud.uni-regensburg.de" class="auth_mail" title="E-mail the corresponding author ; Stefanie M. Klampfl stefanie.klampfl@ur.de" class="auth_mail" title="E-mail the corresponding author ; Oliver J. Bosch ; oliver.bosch@ur.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Arginine-vasopressin ; Maternal aggression ; Maternal care ; Maternal defense test ; Pup retrieval test ; SSR149415 ; V1a receptor ; V1b receptor
- 刊名：Hormones and Behavior
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：79
- 期：Complete
- 页码：18-27
- 全文大小：729 K
文摘
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First study supporting role of V1bR in maternal behavior in relevant brain regions
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No difference in V1bR expression in MPOA or mpBNST between virgin or lactating rats
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Inhibition of V1bR in the MPOA increased maternal motivation to retrieve pups.
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Intra-mpBNST V1bR blockade decreased pup-directed behavior during maternal defense.
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V1bR in distinct brain regions regulate different aspects of maternal behavior.