Vasopressin V1a, but not V1b, receptors within the PVN of lactating rats mediate maternal care and anxiety-related behaviour
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- 作者：Doris S. Bayerl doris.bayerl@ur.de" class="auth_mail" title="E-mail the corresponding author ; Jennifer N. Hö ; nig jennifer.hoenig@live.de" class="auth_mail" title="E-mail the corresponding author ; Oliver J. Bosch ; oliver.bosch@ur.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：ABN ; arched back nursing ; AVP ; arginine-vasopressin ; BNST ; bed nucleus of the stria terminalis ; EPM ; elevated plus maze ; HAB ; high anxiety-related behaviour ; LD ; lactation day ; MPOA ; medial preoptic area ; mPVN ; magnocellular part of the PVN ; PD ; pregnancy day ; pPVN ; parvocellular part of the PVN ; PRT ; pup retrieval test ; PVN ; paraventricular nucleus ; VEH ; vehicle ; V1aR ; V1a receptor ; V1bR ; V1b receptor
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：305
- 期：Complete
- 页码：18-22
- 全文大小：807 K
文摘
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We studied V1 receptors in PVN of lactating rats in maternal behaviour and anxiety.
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V1a receptor blockade decreased nursing and acted anxiolytic.
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V1a receptor blockade did not alter maternal motivation.
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V1b receptor blockade had no effect on any behaviour tested.
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Expression of V1b receptors in PVN was similar in virgin versus lactating rats.