Arsenic impacted the development, thyroid hormone and gene transcription of thyroid hormone receptors in bighead carp larvae (Hypophthalmichthys nobilis)
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- 作者：Hong-Jie Suna ; Ping Xianga ; Ming-Hu Tangb ; Li Sunb ; Lena Q. Maa ; c ; lqma@ufl.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Arsenite ; Arsenate ; Bighead carp ; Early life stage ; Thyroid hormone receptors ; Thyroid hormone
- 刊名：Journal of Hazardous Materials
- 出版年：2016
- 出版时间：13 February 2016
- 年：2016
- 卷：303
- 期：Complete
- 页码：76-82
- 全文大小：1116 K
文摘
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We tested arsenic toxicity on the embryos and larvae of bighead carp.
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We used low levels of AsV and AsIII from 10 to 150 μg L−1.
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Arsenic slightly impacted embryo survival, but greatly decreased larvae survival.
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Arsenic increased thyroid hormone thyroxine in fish larvae by 23–50%.
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Arsenic reduced transcription of thyroid hormone receptors in fish larvae by 53–91%.