Y2 receptor signalling in NPY neurons controls bone formation and fasting induced feeding but not spontaneous feeding
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- 作者：Yue Qi ; y.qi@garvan.org.au" class="auth_mail" title="E-mail the corresponding author ; Melissa Fu ; Herbert Herzog
- 关键词：Neuropeptide Y ; Y2 receptors ; Energy homeostasis ; Bone formation ; Food intake ; Neuropeptides
- 刊名：Neuropeptides
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：55
- 期：Complete
- 页码：91-97
- 全文大小：1251 K
文摘
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Y2 signalling to control NPY plays a critical role in feeding and bone formation.
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NPY specific Y2 deletion increases fasting induced food intake in the first hour.
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NPY specific Y2 deletion decreases bone mineral content.
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Lack of Y2 in NPY neurons increases/reduces NPY and POMC mRNA expression.