Stimulant and motivational effects of alcohol: Lessons from rodent and primate models
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- 作者：Christian Brabanta ; christian.brabant@ulg.ac.be" class="auth_mail ; Douglas J. Guarnierib ; Etienne Quertemonta
- 关键词：6-OHDA ; 6-hydroxydopamine ; ADH ; alcohol dehydrogenase ; ALDH ; acetaldehyde dehydrogenase ; BAC ; blood alcohol concentration ; BAES ; Biphasic Alcohol Effects Scale ; B-BAES ; Brief Biphasic Alcohol Effects Scale ; BXD RI ; recombinant inbred mice ; COF ; consume off the floor ; CPA ; conditioned place aversion ; CPP ; conditioned place preference ; CYP2E1 ; cytochrome P450 2E1 ; D1R ; D2R ; D3R ; and D4R ; dopamine D1 ; D2 ; D3 and D4 receptors ; FAST ; selected mouse line sensitive to the stimulant effects of alcohol
- 刊名：Pharmacology Biochemistry and Behavior
- 出版年：July 2014
- 年：2014
- 卷：122
- 期：Complete
- 页码：37-52
- 全文大小：731 K
文摘
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Several animal species have been used to study alcoholism.
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The present review synthesizes the results obtained in mammalian animal species.
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The review focuses on the stimulant and motivational effects of alcohol.
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Animal species stimulated by alcohol also present features of alcohol addiction.
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The neuronal mechanisms involved in alcohol stimulation and reward are distinct.