Design of a microfluidic strategy for trapping and screening single cells
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- 作者：Paola Occhetta paola.occhetta@polimi.it" class="auth_mail" title="E-mail the corresponding author ; Mara Licini mara.licini@mail.polimi.it" class="auth_mail" title="E-mail the corresponding author ; Alberto Redaelli alberto.redaelli@polimi.it" class="auth_mail" title="E-mail the corresponding author ; Marco Rasponi ; marco.rasponi@polimi.it" class="auth_mail" title="E-mail the corresponding author ; marco.rasponi@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Microfluidics ; Single cell ; High-throughput screening ; Chaotic mixing
- 刊名：Medical Engineering & Physics
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：38
- 期：1
- 页码：33-40
- 全文大小：2255 K
文摘
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A microfluidic platform was designed for single cells trapping.
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Trapping mechanism is based on the automatic variation of hydraulic resistance.
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Presenting platform allowed a single cell trapping efficiency of around 40%.
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A chaotic mixing element was integrated to deliver patterns of particles to cells.