Functional co-activation within the prefrontal cortex supports the maintenance of behavioural performance in fear-relevant situations before an iTBS modulated virtual reality challenge in participants with spider phobia
详细信息 查看全文
- 作者：S. Deppermanna ; 1 ; saskia.deppermann@med.uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author ; S. Notzonb ; 1 ; swantje.notzon@gmail.com" class="auth_mail" title="E-mail the corresponding author ; A. Kroczeka ; Agnes.Kroczek@med.uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author ; D. Rosenbauma ; David.Rosenbaum@med.uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author ; F.B. Haeussingera ; Florian.Haeussinger@med.uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author ; J. Diemerd ; Julia.Diemer@psychologie.uni-regensburg.de" class="auth_mail" title="E-mail the corresponding author ; K. Domschkec ; Domschke_K@ukw.de" class="auth_mail" title="E-mail the corresponding author ; A.J. Fallgattera ; Andreas.Fallgatter@med.uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author ; A.-C. Ehlisa ; Ann-Christine.Ehlis@med.uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author ; P. Zwanzgerb ; 2 ; Peter.Zwanzger@kbo.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Functional connectivity ; Functional near-infrared spectroscopy ; Emotion regulation ; Spider phobia ; Intermittent theta burst stimulation ; Virtual reality
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：307
- 期：Complete
- 页码：208-217
- 全文大小：1586 K
文摘
- •
In spider phobia, left IFG activation is reduced after emotionally irrelevant words.
- •
After phobic words, co-activation was increased between IFG and contra-lateral PFC.
- •
As performance was not impaired, this was interpreted as a compensatory mechanism.
- •
(sham)iTBS/VR leads to activational adjustment between the phobic and control group.
- •
Simultaneously, arousal ratings decreased significantly in the phobic group.