Management of Uncomplicated Acute Appendicitis as Day Case Surgery: Feasibility and a Critical Analysis of Exclusion Criteria and Treatment Failure

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• 作者：Gé ; rard Grelpois ; PhD^a ; ^b ; ^f ; ^g ; ^h ; Charles Sabbagh ; MD ; PhD^a ; ^f ; ⁱ ; ^m ; Cyril Cosse ; PhD^a ; ^b ; ^f ; ^h ; ⁱ ; Brice Robert ; MD^c ; ^j ; Emilie Chapuis-Roux ; MD^a ; ^f ; ^m ; Alexandre Ntouba ; MD^d ; ^k ; Thierry Lion ; MD^e ; ^l ; Jean-Marc Regimbeau ; MD ; PhD^a ; ^b ; ^f ; ^g ; ^h ; ^m ; ^{regimbeau.jean-marc@chu-amiens.fr" class="auth_mail" title="E-mail the corresponding author}
• 关键词：AA ; acute appendicitis ; CAA ; complicated acute appendicitis ; DCS ; day case surgery ; ITT ; intention to treat ; LOS ; length of stay ; NCAA ; uncomplicated acute appendicitis ; PP ; per-protocol
• 刊名：Journal of the American College of Surgeons
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：223
• 期：5
• 页码：694-703
• 全文大小：771 K

文摘

Day case surgery (DCS) for uncomplicated acute appendicitis (NCAA) is evaluated. The objective of this prospective, single-center, descriptive, nonrandomized, intention-to-treat cohort study was to assess the feasibility of DCS for NCAA with a critical analysis of the reasons for exclusion and treatment failures and a focus on patients discharged to home and admitted for DCS on the following day.

Study Design

From April 2013 to December 2015, NCAA patients meeting the inclusion criteria were included in the study. The primary end point was the success rate for DCS (length of stay less than 12 hours) in the intention-to-treat population (all NCAA) and in the per-protocol population (no pre- or perioperative exclusion criteria). The secondary end points were morbidity, DCS quality criteria, predictive factors for successful DCS, patient satisfaction, quality of life, and reasons for pre- or perioperative exclusion. A subgroup of patients discharged to home the day before operation was also analyzed.

Results

A total of 240 patients were included. The success rate of DCS was 31.5% in the intention-to-treat population and 91.5% in the per-protocol population. The rates of unplanned consultations, hospitalization, and reoperation were 13%, 4%, and 1%, respectively. An analysis of the reasons for DCS exclusion showed that 73% could have been modified. For the 68 patients discharged to home on the day before operation, the DCS success rate was 91%.

Conclusions

Day case surgery is feasible in NCAA. A critical analysis of the reasons for exclusion from DCS showed that it should be possible to dramatically increase the eligible population.