Predictors of methadone program non-retention for opioid analgesic dependent patients

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• 作者：Joseph Cox ; M.D. ; M.Sc.^a ; ^b ; ^c ; ^d ; ^{jcox@santepub-mtl.qc.ca} ; Robert Allard ; M.D.C.M. ; M.Sc.^c ; ^d ; Emilie Maurais ; M.Sc.^c ; Noreen Haley^a ; Chris Small ; B.B.A.^a
• 关键词：Treatment retention ; Methadone maintenance program ; Opioid analgesics ; Health care utilization
• 刊名：Journal of Substance Abuse Treatment
• 出版年：2013
• 出版时间：January, 2013
• 年：2013
• 卷：44
• 期：1
• 页码：52-60
• 全文大小：257 K

文摘

This study evaluates loss to follow-up in a methadone maintenance treatment (MMT) program for patients dependent on opioid analgesics in a community in eastern Canada. Data were collected using the Addiction Severity Index Lite. The probability of loss to follow-up was evaluated using a time-to-event analysis. Involuntary and voluntary program discharges were treated separately as the outcomes of interest. Multivariate Cox proportional hazards models were used to explore the role of various patient-related attributes. The probabilities of involuntary and voluntary discharges at 1?year were 20 % and 14 % , respectively. In this exploratory analysis, determinants of loss to follow-up were characteristics related to drug use history (e.g., use of sedatives) and its consequences (e.g., number of lifetime arrests), and differed for each outcome. Some determinants of involuntary discharge were modified by sex. Understanding predictors of specific loss to follow-up outcomes may help MMT programs improve patient retention.