Posterior-anterior gradient of zebrafish hes6 expression in the presomitic mesoderm is established by the combinatorial functions of the downstream enhancer and 3′UTR
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- 作者：Akinori Kawamuraa ; akawamur@mail.saitama-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hiroki Ovaraa ; Yuko Ookaa ; Hirofumi Kinoshitaa ; Miki Hoshikawaa ; Kenji Nakajoa ; Daisuke Yokotaa ; Yuuri Fujinoa ; Shin-ichi Higashijimab ; Shinji Takadac ; Kyo Yamasua
- 关键词：Somite ; Hairy-related gene ; Expression gradient ; Transcriptional regulation ; 3&prime ; UTR ; Zebrafish
- 刊名：Developmental Biology
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：409
- 期：2
- 页码：543-554
- 全文大小：4245 K
文摘
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Identification of the transcriptional regulatory region of zebrafish hes6 (PT enhancer).
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T-box and Ets transcription factors bind to and regulate the PT enhancer.
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PT enhancer with 3′UTR of hes6 recapitulates gradient of hes6 expression in the PSM.