Implant supported dental rehabilitation following segmental mandibular reconstruction- quality of life outcomes of a prospective randomized trial

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• 作者：Vinay V. Kumar^a ; ^b ; ^{veezo@rediffmail.com" class="auth_mail" title="E-mail the corresponding author} ; P.C. Jacob^a ; ^{pcjacob66@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Supriya Ebenezer^c ; ^{supriyaebenezer@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Moni A. Kuriakose^a ; ^{makuriakose@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Vikram Kekatpure^a ; ^{kvikram2000@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Amresh S. Baliarsing^d ; ^{amresh_baliarsing@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Bilal Al-Nawas^b ; ^{Al-Nawas@uni-mainz.de" class="auth_mail" title="E-mail the corresponding author} ; Wilfried Wagner^b ; ^{wilfried.wagner@unimedizin-mainz.de" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Dental implants ; Free fibula flap ; Quality of life ; Oral cancer ; Rehabilitation ; Mandible reconstruction
• 刊名：Journal of Cranio-Maxillofacial Surgery
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：44
• 期：7
• 页码：800-810
• 全文大小：3068 K

文摘

The primary objective of this study was to assess the difference in quality of life (QoL) in patients with dental rehabilitation using two or four implant-supported overdentures following segmental mandibulectomy defect reconstruction with fibula free flap.

Material and methods

This prospective, parallel designed, randomized clinical study was conducted with a 1:1 ratio. At baseline, all participants already had fibula flap reconstruction for segmental defects of the mandible and rehabilitation with conventional (non-implant supported) removable partial dentures. The participants were then randomized into two groups. Group I received implant supported overdentures on two implants, and Group II received four implants. QoL outcomes were evaluated using standardized questionnaires (EORTC_QLQ c30, H&N35, OHIP, DSI). Outcomes of treatment were evaluated at 6 months (T1) and 1 year (T2) following rehabilitation.

Results

A total of 52 patients were randomized into two treatment groups (26 each). After accounting for the loss to lack of follow-up, 22 patients in Group I and 24 patients in Group II were evaluated for QoL at the end of the study. There was a significant improvement in QoL with implant-assisted dental rehabilitation. However there were no significant differences in QoL between the two-implant and four-implant groups.

Conclusion

Implant-supported removable overdentures improve QoL outcomes in patients with reconstructed mandibles. This study showed no significant difference in QoL outcomes in patients with two- or four-implant supported removable prostheses.