{Ru^II(NO⁺)}³⁺-core complexes with 4-methyl-pyrimidine and ethyl-isonicotinate: Synthesis, X-ray structure, spectroscopy, and computational and NO-release studies upon

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• 作者：Gabriella Tamasi ; Matia Curci ; Francesco Berrettini ; Nicholas Justice ; Aless ; ro Sega ; Luisa Chiasserini ; Renzo Cini
• 关键词：Ruthenium ; Nitric oxide ; Pyrimidine ; Isonicotinate ; Photo-reactivity
• 刊名：Journal of Inorganic Biochemistry
• 出版年：2008
• 出版时间：October 2008
• 年：2008
• 卷：102
• 期：10
• 页码：1874-1884
• 全文大小：859 K

文摘

The reaction of RuCl₃(NO) · H₂O with 4-methylpyrimidine (MePYM) and ethylisonicotinate (EINT), in absolute ethanol at 40–55 °C afforded crystalline trans-[RuCl₃(NO)L₂] complexes. Structural studies via X-ray diffraction, and spectroscopic methods (NMR, IR, UV–visible (UV–Vis)) revealed that the molecular structures have the two Ls in trans positions (axial) and the chloride anions and the NO⁺ cation as equatorial ligands; pyrimidinepyrimidine pairing pattern via two weak C–HN interactions occur. The molecular structures for the EINT derivative was inferred from spectroscopy and computations. Under irradiation at 366 nm several solutions of the title compounds deliver NO via first order processes. Visible light (420–700 nm) does not produce significant NO release from CH₂Cl₂ and CH₃CN solutions within 24 h.