- 作者：Julia Carrasco-Valiente ; Juan Pablo Campos-Hern谩ndez ; Jes煤s Ruiz-Garc铆a ; Francisco Javier M谩rquez-L贸pez ; Mar铆a Jos茅 Requena-Tapia ; Rafael Prieto-Castro
- 关键词：Prostatectomí ; a radical ; Disfunció ; n eré ; ctil ; Prostaglandina E1 ; Ecodoppler
- 刊名：Revista Internacional de Androlog铆a
- 出版年：January-March, 2014
- 年：2014
- 卷：12
- 期：1
- 页码：4-9
- 全文大小：478 K
Objectives
Primary: to evaluate the importance of early rehabilitation of the corpus cavernosum on erectile function after radical prostatectomy. Secondary: to analyse the factors associated with better response.
Material and method
Retrospective study in patients treated with intracavernous injections after radical prostatectomy between 1 January 2006 and 31 December 2008. We included patients lacking a history of erectile dysfunction prior to surgery, not responding to phosphodiesterase-5 inhibitors. All patients underwent colour echo-doppler after injection of prostaglandin E1 10-20 mg. The outcomes of these 2 groups were then compared according to how early rehabilitation began after surgery (early, < 6 months, or late, > 6 months).
Results
There were 82 patients included in the study. In the multivariate analysis, predictive factors of good response to treatment were: early onset of rehabilitation (OR: 0.06; 95% CI: 0.014-0.26), higher peak systolic velocity during the test (OR: 1.01; 95% CI: 1.01-1.1) and favourable histopathological stage (OR: 0.15; 95% CI 95%: 0.036-0.6). The colour echo-doppler procedure after prostaglandin E1 injection showed abnormal values more frequently in the late-onset than in the early group (89.5% [n = 34] vs. 65.9% [n = 29];
Conclusions
According to this study, early erectile dysfunction rehabilitation after radical prostatectomy achieves better results than late rehabilitation in patients.