In vitro antimicrobial susceptibility of Alloscardovia omnicolens and molecular mechanisms of acquired resistance
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- 作者：Christophe Isnarda ; b ; Reto Lienhardc ; Sophie Reissiera ; Sonia Rodriguezc ; Joanna Krä ; henbü ; hld ; Nadia Liassinee ; Franç ; ois Gué ; rina ; b ; f ; Vincent Cattoira ; b ; f ; cattoir-v@chu-caen.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：A. omnicolens ; Macrolide resistance ; 23S rRNA mutation ; Fluoroquinolone resistance ; QRDR ; parC mutation
- 刊名：Diagnostic Microbiology & Infectious Disease
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：84
- 期：3
- 页码：227-229
- 全文大小：379 K
文摘
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All A. omnicolens isolates exhibited low MICs for all β-lactams, glycopeptides, linezolid, tetracyclines, and cotrimoxazole.
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MICs ≥256 mg/L for erythromycin and clindamycin associated with a single point mutation in 23S rRNA.
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Acquired fluoroquinolone resistance (1 isolate) likely related to a mutation in ParC (Ser80Phe).