Impulse control and restrained eating among young women: Evidence for compensatory cortical activation during a chocolate-specific delayed discounting task

详细信息    查看全文

• 作者：Debo Dong^a ; ^b ; ^c ; ¹ ; ^{debo.dong@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Yulin Wang^a ; ^b ; ^d ; ¹ ; ^{lingzhen1314gogo@163.com" class="auth_mail" title="E-mail the corresponding author} ; Todd Jackson^a ; ^b ; ^e ; ^{toddjackson@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Shuaiyu Chen^a ; ^b ; ^{chenshuaiyu3@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Yu Wang^a ; ^b ; ^{wangyu.swu@foxmail.com" class="auth_mail" title="E-mail the corresponding author} ; Feng Zhou^c ; ^{fengzhou.uestc@outlook.com" class="auth_mail" title="E-mail the corresponding author} ; Hong Chen^a ; ^b ; ^{chenhg@swu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Restrained eating ; Compensatory effect ; Impulse-control ; DLPFC ; Functional magnetic resonance imaging
• 刊名：Appetite
• 出版年：2016
• 出版时间：1 October 2016
• 年：2016
• 卷：105
• 期：Complete
• 页码：477-486
• 全文大小：1405 K

文摘

Theory and associated research indicate that people with elevated restrained eating (RE) scores have higher risk for binge eating, future bulimic symptom onset and weight gain. Previous imaging studies have suggested hyper-responsive reward brain area activation in response to food cues contributes to this risk but little is known about associated neural impulse control mechanisms, especially when considering links between depleted cognitive resources related to unsuccessful RE. Towards illuminating this issue, we used a chocolate-specific delayed discounting (DD) task to investigate relations between RE scores, behavior impulsivity, and corresponding neural impulse control correlates in a functional magnetic resonance imaging (fMRI) study of 27 young women. Specifically, participants were required to choose between more immediate, smaller versus delayed, larger hypothetical chocolate rewards following initial consumption of a chocolate. As predicted, RE scores were correlated positively with behavior impulse control levels. More critically, higher RE scores were associated with stronger activation in impulse control region, the dorsal-lateral prefrontal cortex (DLPFC) during the completion of difficult decision trials reflecting higher cognitive demands and resource depletion relative to easy decision trials. Exploratory analyses revealed a positive correlation between RE scores and activity in a reward system hub, the right striatum. Moreover, a positive correlation between left DLPFC and striatum activation was posited to reflect, in part, impulse control region compensation in response to stronger reward signal among women with RE elevations. Findings suggested impulse control lapses may contribute to difficulties in maintaining RE, particularly when cognitive demands are high.