The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study
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- 作者：Andrew Croziera ; b ; Bojan Blazevica ; Pablo Lamataa ; Gernot Plankb ; Matthew Ginksc ; Simon Duckettc ; Manav Sohalc ; Anoop Shettyc ; Christopher A. Rinaldic ; Reza Razavia ; Nicolas P. Smitha ; d ; Steven A. Niederera ; steven.niederer@kcl.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：AHR ; acute haemodynamic response ; CRT ; cardiac resynchronisation therapy ; DCM ; dilated cardiomyopathy ; ECG ; electrocardiogram ; EF ; ejection fraction ; EP ; electrophysiology ; HF ; heart failure ; LBBB ; left bundle branch block ; LV ; left ventricle ; MRI ; magnetic resonance imaging ; NCM ; non-contact mapping ; QRSd ; QRS duration ; RV ; right ventricle ; SR ; sinus rhythm ; TAT ; total activation time of the ventricles ; VPC ; virtual patient cohort
- 刊名：Journal of Molecular and Cellular Cardiology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：96
- 期：Complete
- 页码：93-100
- 全文大小：1294 K
文摘
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Ventricular conduction block indicates patient response to CRT.
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Placement of CRT pacing leads strongly affects response to therapy.
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Improved treatment planning should be prioritised in order to maximise CRT outcomes.